Causes of Mesothelioma - Non Asbestos Causes of Mesothelioma
Many people who have had asbestos exposure for long periods may develop mesothelioma. Exposure could be secondhand, occupational, or environmental.
Mesothelioma can cause damage to the linings of several organs like the pleura, the heart lining, the tunica vaginalis and the pericardium. what causes mesothelioma other than asbestos could take up to 50 years for mesothelioma signs to show.
1. Genetics
Exposure to asbestos can trigger mesothelioma by irritating the cells that line organs of the body. The type of mesothelioma varies on the manner in which asbestos fibers come into contact with the cells. Asbestos-related mesothelioma symptoms usually occur between 20 and 60 years after the initial exposure. The genetic makeup of a person may play a part in developing asbestos-related cancer.
A gene mutation could alter the way that cells make proteins. The proteins can be under-expressed or over-expressed. The over-expression of these proteins causes the development of cancerous tumors.
Most mesothelioma cases are caused by asbestos exposure. However, studies are showing that genetics and other factors play a part in mesothelioma development.
Scientists have identified mutations that increase risk of mesothelioma. This includes the BAP1 gene as well as the LATS2 gene. Both of these genes are involved in controlling mesothelial cell growth and repair. A mutation in the BAP1 gene can lead to mesothelial cells being over-expressed.
The risk of developing mesothelioma increases with age. This is due to asbestos being used more often in the workplace before the 1980s in the beginning. However, some people who were exposed to asbestos as teenagers and children have developed mesothelioma later in their lives.
Researchers are studying the possible connection between mesothelioma and cancer. One study examined five case-control studies. Four of the studies utilized patients with non-asbestos-related cancers as control subjects. One study, which focused specifically on pancreatic cancer, excluded Mesothelioma patients. These studies show that mesothelioma can be caused by genetics, other cancers, and asbestos exposure.
2. Alcoholism
Mesothelioma can begin in the tissue covering the organs of the abdomen (peritoneal mesothelioma of the peritoneal region) or in the tissue that covers the lung tissue (pleural pleural mesothelioma). The most common reason for mesothelioma's development is exposure to asbestos. Other factors can increase your risk, such as working in areas that have asbestos levels that are high (like shipyards), the family history or genetic traits that are linked to asbestos-related diseases, and working in places where there is a lot of asbestos.
Asbestos is a mineral that occurs naturally, is made up of microscopic and strong fibers. It was used in the production of dozens of construction products between the 1930s and the 1980s because it was resistant to fire, water or sound. Workers who handled or exposed to the material were usually unaware of the dangers associated with it. People who lived near workers may have also been exposed to the fibers through secondhand smoke.
Mesothelioma is caused by asbestos exposure. It damages the cells that surround each organ. The asbestos fibers get trapped in the lining of the organ and break or damage the thin tissue. In time the piercing and disintegration cause scarring that forms tumors.
There is no cure for mesothelioma but you can receive treatment to alleviate symptoms and prolong your life. Treatment options like chemotherapy, surgery and radiation therapy are a few of the best treatments.
Asbestos is now recognized as the only cause of mesothelioma. If you have a family history or a history of asbestos exposure, you should consult your doctor if any symptoms develop. Early detection can offer the most effective treatment.
3. Smoking
Although it doesn't cause mesothelioma directly, smoking introduces carcinogens into the lungs, which can contribute to asbestos exposure and increase the risk of developing asbestos cancer. This is especially true for those diagnosed with pleural mesothelioma, which forms close to the lungs. Inhaling asbestos fibers and affected lung tissue can cause cancer and trigger its growth.
Mesothelioma is linked to asbestos exposure. Asbestos is a mineral that occurs naturally that is composed of strong, microscopic fibres. It was utilized in a variety of different construction and industrial products from the 1930s to the 1980s due to its resistance to fire and water as well as sound. The manufacturers were aware of the dangers but did not inform the public.
Asbestos can be exposed in many ways, like working on a ship or aircraft that contains asbestos. Even exposure to asbestos from secondhand sources can cause the disease, such as bringing fibers of asbestos home on hair or clothing.
asbestos workers or veterans who have been exposed to asbestos for an extended time are at greater risk of developing mesothelioma. Mesothelioma is still a possibility for those who have had only one or two exposures to asbestos. Mesothelioma tends to develop in the lungs, but it can also grow in the stomach's lining (peritoneal mesothelioma) and in the membrane surrounding the testes (pericardial mesothelioma).
It could take up to 50 years for mesothelioma symptoms to be discovered following a person's previous asbestos exposure. Because asbestos is extremely dangerous people who have experienced any asbestos exposure should ask their physician about the possibility of developing mesothelioma. If asbestos exposure is the reason of mesothelioma, a specialist must be involved in the treatment process to achieve the greatest outcomes.
4. Drugs
Exposure to asbestos is the most frequent cause of Mesothelioma. Asbestos is made up of microscopic fibers, and is a mineral that occurs naturally. It was used in a variety of industries before it was banned in 1999. It is resistant to heat, water and sound. People exposed to asbestos frequently breathe in these fibres and they can remain in the lung for a long period of time, which leads to damage to. The lungs that have been damaged can develop cancerous tissues and mesothelioma. The most prevalent mesothelioma type is pleural mesothelioma, which affects the lining of the lung. Asbestos exposure can also cause peritoneal cancer, which is found in the stomach lining.
Mesothelioma symptoms usually don't appear until 20 or 60 years after exposure to asbestos. This is known as the latency time of asbestos. Symptoms of mesothelioma include breathing problems and chest pain. If you are experiencing mesothelioma-related symptoms, you need to consult a specialist for diagnosis and a testing. General oncologists could misdiagnose the cancer, and you could be offered unnecessary treatments.
Some people have a greater risk of developing mesothelioma compared to others. These can be caused by an asbestos-related history or family history, as well as genetic predisposition. The asbestos-related workers are more likely to develop pleural mesothelioma than people who do not. Workers may carry asbestos fibres back home on their clothing. Women who have been a part of a marriage with a man who was exposed to asbestos are also at risk of developing peritoneal mesothelioma. This is because they could have knowingly ingested asbestos fibres on their clothing.
Other risk factors for mesothelioma include a family history, being a male and having received radiation treatment for another disease. These factors cannot be altered however, you can decrease your risk by reducing the amount you breathe in of asbestos, being aware of asbestos exposure and following your doctor's advice regarding treatment.
5. Alcohol
Asbestos is the leading cause of mesothelioma. The carcinogen found in certain minerals can cause cancer when people inhale or swallow it. It can also get into the body through contact with skin and clothing. Workers are exposed to asbestos fibers when they cut, sand, or scrape surfaces on buildings or ships that contain asbestos. The asbestos fibers are released into the air, where others in the area can inhale them or ingest them.
The stomach's lining and chest cavity may also be affected by mesothelioma. Men are more likely to develop pleural mesothelioma because of their exposure to asbestos at work. However, women who lived with asbestos-exposed husbands are more likely to develop peritoneal mesothelioma. This could be due to the fact that the wives carried asbestos back home on their clothes or hair.
The symptoms of mesothelioma are shortness of breath, coughing, chest pain and abdominal swelling. Other symptoms include fatigue, weight loss, and fever. A lot of these symptoms are similar to those of other diseases, which is why mesothelioma is frequently misdiagnosed.
The only way to avoid mesothelioma is to avoid exposure to asbestos. If you are already suffering from the disease there are ways to increase your odds of a better prognosis. A doctor can examine mesothelioma symptoms and request blood tests or imaging scans. These could include CT, MRI and PET scans. A biopsy is the most effective method to confirm a diagnosis and rule out any other ailments. The procedure can be performed by a specialist in thoracic surgery. Doctors can assist you in finding a specialist near you. They can also help you learn about your treatment options.